Does L-Arginine Help With Erectile Dysfunction?

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Written By Mikael

Fact Checked & Written as per the Editorial Process.

In this article, we will look at L-Arginine and whether this amino acid helps with Erectile Dysfunction in men.

Erectile dysfunction (ED) is a common condition affecting millions of men worldwide. It refers to the inability to achieve or maintain an erection sufficient for sexual intercourse.

While there are several treatments available for ED, many men are turning to natural supplements, such as L-arginine, to help improve their symptoms.

L-Arginine alone may not be effective in treating ED. But, supplements made with a combination of l-arginine and other ingredients can help fix erectile dysfunction in men. Cilexin is one such supplement.

What is L-Arginine?

L-arginine is a semi-essential amino acid that plays a crucial role in the production of proteins in the body.

L-arginine is converted into nitric oxide (NO) through a process known as nitric oxide synthase (NOS) enzymatic reaction.

Nitric oxide acts as a signalling molecule that helps to relax and dilate blood vessels, thereby improving blood flow to various tissues and organs throughout the body.

This is particularly important for the health of the cardiovascular system and erectile function, as healthy blood flow to the arteries of the penis is essential for normal erectile function.

Is Low L-Arginine The Reason For Your ED Problem?

Erectile Dysfunction can be caused due to multiple reasons and low levels of L-Arginine can be one of them. If you have the following symptoms then it is quite possible that L-Arginine is the reason for your ED problem.

Poor circulation

L-arginine is involved in the production of nitric oxide, which helps to relax and widen blood vessels. Low levels of L-arginine may therefore lead to poor circulation, which can cause symptoms such as cold hands and feet, numbness, and tingling.

Fatigue and weakness

L-arginine is important for energy production and muscle metabolism. Low levels of L-arginine may therefore lead to fatigue, weakness, and poor exercise performance.

Poor wound healing

L-arginine is involved in the healing of wounds and injuries. Low levels of L-arginine may therefore lead to slow or poor wound healing, as well as an increased risk of infection.

High blood pressure

L-arginine is involved in the regulation of blood pressure through its effects on nitric oxide production and blood vessel function. Low levels of L-arginine may therefore contribute to high blood pressure.

Erectile Dysfunction and L-Arginine – The Relation

Nitric Oxide is a vasodilator that is important for improving blood flow. A good blood flow to the penis helps in maintaining an erection.

Whenever you are sexually aroused, the brain sends a signal to the tissue inside the penis. The dilation of the blood vessels inside the penis results in an erection.

Men with ED issues have problems with blood circulation inside the penis and an increase in nitric oxide levels is necessary to fix this.

L-Arginine helps in increasing the levels of nitric oxide in the body which may result in fixing ED.

In 2019, a review published by the Journal of Psychosexual Health found that positive evidence is available for the efficacy of l-arginine and its various combinations in the treatment of erectile dysfunction.

However, further research with larger sample sizes and standardized tools is required to recommend the routine use of these products in the treatment of erectile dysfunction.

This means that l-arginine alone may not cure ED in men but it can be effective when used in combination with other ingredients. One such supplement that includes l-arginine and other male enhancement ingredients is Cilexin.

A 2003 clinical trial concluded that oral administration of L-arginine in combination with Pycnogenol causes a significant improvement in sexual function in men with ED without any side effects.

Other Benefits of L-Arginine

Although l-arginine is commonly known for its use in treating erectile dysfunction, it also offers other health benefits that many people may not be aware of.

  • Supports cardiovascular health by improving blood flow and reducing blood pressure.
  • Enhances immune system function, which can help fight off infections and diseases.
  • Promotes athletic performance by increasing blood flow and oxygen delivery to muscles, reducing fatigue and improving endurance.
  • Improves insulin sensitivity, which can be useful for managing conditions such as diabetes.
  • Aids in wound healing by promoting tissue repair and regeneration.
  • May reduce inflammation throughout the body, which is linked to a range of health issues.
  • Helps to support healthy kidneys and liver function.
  • Supports the production of growth hormone, which is essential for muscle growth and repair.
  • May have benefits for mental health, including reducing stress and anxiety levels.
  • Can help to improve fertility in both men and women.

Overall, l-arginine is a versatile amino acid that offers a range of benefits for physical and mental health, making it a valuable addition to a healthy lifestyle.

Natural Sources of L-Arginine

Increasing your levels of l-arginine may help with ED. If you are looking for natural sources of l-arginine, here is the list.

  • Meat and Poultry: Beef, pork, chicken, and turkey are all good sources of L-arginine.
  • Seafood: Fish and shellfish are also good sources of L-arginine. Some of the best sources include tuna, salmon, and shrimp.
  • Dairy Products: Milk, cheese, and yogurt are all good sources of L-arginine.
  • Nuts and Seeds: Peanuts, walnuts, almonds, sunflower seeds, and pumpkin seeds are all good sources of L-arginine.
  • Legumes: Beans, lentils, and soybeans are also good sources of L-arginine.
  • Grains: Oats, wheat, and rice are all good sources of L-arginine.
  • Vegetables: Spinach, kale, and other leafy greens are good sources of L-arginine, as are beets and carrots.

Side Effects of L-Arginine

Some of the potential side effects from l-arginine include:

  • Abdominal pain
  • Bloating
  • Diarrhea
  • Gout
  • Low blood pressure
  • Nausea
  • Allergic reactions, such as rash or hives

Supplements and medications can come with side effects. These side effects vary from person to person and can be caused due to various reasons.

One of the main reasons for any of the side effects can be the medication you are on. Your existing medication can react with l-arginine to cause such side effects.

Hence, it is always recommended to talk to a medical practitioner before taking any supplements.


L-Arginine increases nitric oxide levels in the body which improves blood flow to the penis. This increased blood flow may help with maintaining erections.

There is very little evidence that L-Arginine alone may help with erectile dysfunction. Supplements that have a combination of l-arginine along with other potent ingredients have shown better results when it comes to treating erectile dysfunction.

One such supplement that claims to treat ED is Cilexin.

Is Cilexin the right supplement for you? Read my Cilexin review.

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